Do Muscle Cells "Talk" To Fat? YES!! NOW THERE'S PROOF!!

We already know that exercising reduces body fat.  But how does that happen?  How do muscle cells "talk" to fat...  and how much of a role does exercise have in it?  For a long time, scientists theorized about it, but now there is proof of a hormone:  PGC1-alpha is that messenger.  
The New York Times just published this interesting article about this newly discovered hormone and how it effects us at the cellular level...  

Exercise Hormone May Fight Obesity and Diabetes

By GRETCHEN REYNOLDS

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A newly discovered hormone produced in response to exercise may be turning people’s white fat brown, a groundbreaking new study suggests, and in the process lessening their susceptibility to obesity, diabetes and other health problems. The study,published on Wednesday in Nature and led by researchers at the Dana-Farber Cancer Institute and Harvard Medical School, provides remarkable new insights into how exercise affects the body at a cellular level.

For the study, the researchers studied mouse and human muscle cells. Scientists have believed for some time that muscle cells influence biological processes elsewhere in the body, beyond the muscles themselves. In particular, they have suspected that muscle cells communicate biochemically with body fat.

But how muscle cells “talk” to fat, what they tell the fat and what role exercise has in sparking or sustaining that conversation have been mysteries — until, in the new study, scientists closely examined the operations of a substance called PGC1-alpha, which is produced in abundance in muscles during and after exercise.

“It seems clear that PGC1a stimulates many of the recognized health benefits of exercise,” said Bruce Spiegelman, the Stanley J. Korsmeyer professor of cell biology and medicine at the Dana-Farber Cancer Institute and Harvard Medical School, who led the study. Mice bred to produce preternaturally large amounts of PGC1a in their muscles are typically resistant to age-related obesity and diabetes, much as people who regularly exercise are......CLICK HERE TO READ THE REST OF THE ARTICLE!!!